Research Areas with Select Publications
For full list of publications, please see Dr. Priya S Balasubramanian’s Google Scholar
Neural and Biological Interfaces
Novel devices with the next generation in spatiotemporal resolution tested for rapid biomedical translation with conscientious methodologies using human cell and tissue culture techniques.
Balasubramanian, P.S. and Lal, A., 2018, October. Cellular Localization and Dosage Regulation of Neural Stimulation Enabled by 1.05 GHz Ultrasonics. In 2018 IEEE International Ultrasonics Symposium (IUS) (pp. 1-4). IEEE. link
Balasubramanian, P.S., Singh, A., Xu, C. and Lal, A., 2020. GHz Ultrasonic chip-Scale Device induces ion channel Stimulation in Human neural cells. Scientific reports, 10(1), pp.1-20. link
Balasubramanian, P.S., 2021. Characterization of SH-SY5Y Neurons Subject to 92kHz Ultrasound Stimulation. Int. J. Morphol, 39(4), pp.1109-1115. link
Device Development
Integration, multimodal utilities, process development, and materials for the next generation in micro nano systems engineering.
P. S. Balasubramanian and A. Lal, "GHz Ultrasound and Electrode Chip-Scale Arrays Stimulate and Influence Morphology of Human Neural Cells," in IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, doi: 10.1109/TUFFC.2022.3152427. link
Clinical Impact
Clinical connections, collaborations, and human subjects research towards better outcomes and personalized medicine.
Wu, G., Li, R.R., Balasubramanian, P.S., Li, M.M., Yang, K., Huang, W.Y. and Chen, F., 2020. Temporal lobe microstructural abnormalities in patients with nasopharyngeal carcinoma quantitatively evaluated by high-resolution DWI and DKI after concurrent chemoradiotherapy. Clinical and translational radiation oncology, 21, pp.36-43. link
Wu, G., Luo, S.S., Balasubramanian, P.S., Dai, G.M., Li, R.R., Huang, W.Y. and Chen, F., 2020. Early Stage Markers of Late Delayed Neurocognitive Decline Using Diffusion Kurtosis Imaging of Temporal Lobe in Nasopharyngeal Carcinoma Patients. Journal of Cancer, 11(20), p.6168. link
Wu, G., Huang, W., Xu, J., Li, W., Wu, Y., Yang, Q., Liu, K., Zhu, M., Balasubramanian, P.S. and Li, M., 2021. Dynamic contrast-enhanced MRI predicts PTEN protein expression which can function as a prognostic measure of progression-free survival in NPC patients. Journal of Cancer Research and Clinical Oncology, pp.1-10. link
Huang, W., Liu, T., Chen, H., Fu, Q., Fu, L., Xu, X., Liu, L., Guo, Y., Balasubramanian, P.S. and Chen, F., 2022. Mapping white matter structural and network alterations in betel quid-dependent chewers using high angular resolution diffusion imaging. Frontiers in Psychiatry, 13, p.1036728. link
Sensors
CMOS compatible, high resolution and high sensitivity microsystems for sensing nanoscale properties with biological applications in mind.
Balasubramanian, Priya S., and Amit Lal. "GHz Ultrasonic Sensor for Ionic Content with High Sensitivity and Localization." iScience (2023). link
Mathematics
Computational techniques and algorithms for biophysical signal reconstruction from both novel sensors and commercially available devices.
Balasubramanian, P.S., Spincemaille, P., Guo, L., Huang, W., Kovanlikaya, I. and Wang, Y., 2020. Spatially Adaptive Regularization in Total Field Inversion for Quantitative Susceptibility Mapping. Iscience, 23(10), p.101553. link
Li, H., Huang, W., Wang, S., Balasubramanian, P.S., Wu, G., Fang, M., Xie, X., Zhang, J., Dong, D., Tian, J. and Chen, F., 2023. Comprehensive integrated analysis of MR and DCE-MR radiomics models for prognostic prediction in nasopharyngeal carcinoma. Visual Computing for Industry, Biomedicine, and Art, 6(1), p.23. link
And more!
Working on exciting science for important causes
Conservation technology, sustainable engineering, energy harvesting technology, biological discoveries …